Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Abstract Chronic obstructive pulmonary disease (COPD) and sleep apnoea (OSA) syndrome (OSAS) are both common conditions. Their comorbid association – overlap (OVS) can result in clinically important nocturnal oxygen desaturation. We sought to compare demographic anthropometric characteristics, associated comorbidities saturation patients with OVS versus OSA alone. Methods included consecutive diagnosed our laboratory. Overnight studies were performed, data regarding prevalence of somnographic parameters compared for A P value <0.05 was considered significant. Results total 2173 assessed, whom 381 (17.5%) had OVS. Significant differences found between the groups all evaluated parameters. Conclusions older, predominantly male, a higher cardiovascular metabolic comorbidities, worse apnoea–hypopnoea index (AHI)